Peripheral Pathology in the Lewy Body Dementias (R01 Clinical Trial Not Allowed)

Peripheral Pathology in the Lewy Body Dementias (R01 Clinical Trial Not Allowed)

Annoucement Type:
New
Activity Code:
R01
FOA Number:
RFA-NS-20-014
Application Due Date:
Contact:
Debra Babcock, PhD, MD

Funding Opportunity Purpose

The purpose of this initiative is to identify potential diagnostic markers for the Lewy Body Dementias using non-blood or non-CSF peripheral specimens and tissues (e.g., skin, salivary gland, gastrointestinal tract, etc.). Blood and CSF have traditionally and extensively been examined for neurodegenerative disease biomarkers; however, research suggests that abnormal alpha-synuclein accumulation occurs in other peripheral tissues and specimens early in the disease course and may provide opportunities for early diagnosis and future treatment development.